A clinical trial shows those with diabetes given the drug Jardiance were 38% less likely to die from a heart attack, stroke or other cardiovascular disease.

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It’s an unfortunate truth, but diabetes is one of the leading causes of cardiovascular diseases and stroke. In fact, people with Type 2 diabetes are five to eight times more likely to develop cardiovascular disease, and to suffer a fatal heart attack or stroke.

Good News

Until recently, there has been little progress made in developing a drug that could reduce this risk. Prospects are brighter however with the release of results from a clinical trial ordered by the Federal Drug Administration. The New England Journal of Medicine published results last month that showed individuals who were given the blood sugar-lowering drug Jardiance were 38% less likely to die as a result of a heart attack, stroke or other cardiovascular issue than those given a placebo.

Also, those taking Jardiance were 35% less likely to be hospitalized for heart failure than those who took the placebo. Both findings bode well for diabetes sufferers.

Significant, Surprising Results

The results are surprising to many in the medical community as previous drug trials have not had a significant impact on reducing death from cardiovascular disease and stroke for those with diabetes. The clinical trials sponsored by Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly and Co., suggest that among diabetes patients with cardiovascular disease, 39 people would have to be treated to prevent one premature death. This “number-to-treat” ratio puts the drug’s effectiveness on the same level as cholesterol-lowering statins and maybe even ahead of blood pressure medications.

Jardiance reduces blood sugar in diabetes patients by helping eliminate it from their urine. In all, 8.3% of the people taking the placebo died of any cause during the course of the study, compared with 5.7% of the people taking Jardiance.

Bright Prospects

Although the findings of the study are surprising to many, it is encouraging to see progress made in reducing one of the leading causes of death for those with diabetes.

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