Posted on May 19, 2011 by Joel Shpigel R.Ph.

Master Switch Gene Found That Could Regulate Diabetes and Obesity

Scientists have found a  a "master switch gene" that  turns other genes found in fat in the body off and on. Professor Tim Spector, study leader from the Department of Twin Research at King's College London said that since fat plays an important role in peoples' susceptibility to metabolic diseases like obesity, heart disease and Diabetes, the regulating gene could be target for drugs to treat such illnesses.

 KLF14 has been linked to Type 2 Diabetes and cholesterol levels in previous studies.  Professor Mark McCarthy of Oxford University, co-author of the study says that "KLF14 seems to act as a master switch controlling processes that connect changes in the behavior of subcutaneous fat to disturbances in muscle and liver that contribute to diabetes and other conditions."  

 

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