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Diabetes Pharmacist Answers Your Medication Dosing Questions
At Focus Express Mail Pharmacy, we are asked many questions everyday, by our patients, regarding their medications. Our pharmacists answer questions regarding dosing, interactions, side effects, and more. We will try, on a weekly basis, to share some of those questions with you that we feel are most interesting, informative, and educational.
Overwhelmingly the most questions that we get involve dosing. Below are some common questions and their answers. Glad we can help!
What does twice daily mean?
A: Take your dose twice during the 24-hour day, which means every 12 hours. For example, take one dose at 7 a.m. and one dose at 7 p.m.
What does three times a day mean?
A: Take your dose three times during the 24-hour day, which means every eight hours. For example, take one dose at 7 a.m., another at 3 p.m., and the last at 11 p.m. (or at bedtime, if you go to sleep before 11 p.m.).
What exactly does four times a day mean?
A: Take your dose four times during during your waking hours, about six hours apart.
What does two tablets daily mean?
A: Take two tablets at the same time once a day.
What does two tablets twice daily mean?
A: Take two tablets every 12 hours, for a total of four tablets each day.
What does the medicine label mean when it says to take at bedtime?
A: It usually means take it 30 minutes to one hour before bedtime.
What does take with food mean?
A: It means to take the dose during the meal or right after eating a meal.
What does take on an empty stomach mean?
A: It usually means to take the dose at least one hour before or two to three hours after eating.
Sources:
Mayo Clinic Family Health Book. William Morrow & Co., 1996.
Applied Therapeutics: The Clinical Use of Drugs. Applied Therapeutics, 1995.
New Class of Drugs May Treat or Prevent Diabetes
Robert Langreth, in Forbes.com, writes about a new type of drug, called an anti-CD3 antibody, which aims for the first time to delay or prevent development of diabetes by arresting the immune system's attack on pancreatic islet cells. This new class of drugs, now entering final-stage human trials, are given to newly diagnosed patients for just a few days or weeks but appear to preserve some insulin-producing capacity for years. Ultimately the drugs may even be able to prevent the disease from striking people at high risk because of a family history of diabetes or bad genes. MORE.....
Fiber in Your Diet Aids in Diabetes Prevention
According to Emilie LeBeau in the Chicago Tribune, among fiber's substantial benefits are weight control, lower cholesterol and diabetes prevention.
Adding fiber to your daily diet can be as simple as switching from processed to fresh foods. For people who avoid grains,fruits such as apples, berries, oranges, pears and prunes are high in fiber. Vegetables such as beans, broccoli, Brussels sprouts, cauliflower, carrots and peas also are high in fiber. More......
Type 1 Diabetes Caused by T-Cell Impotence
T-cells suppress and regulate the body's immune responses, but in diabetes mellitus, or type 1 diabetes, the body's own immune system attacks and destroys insulin-producing islet cells in the pancreas. Patients must thereafter inject insulin daily.
"The genetic and cellular mechanisms by which the immune system goes out of control and destroys the islets has been an enigma and an area of great interest over the last few decades," said Dr. Ciriaco Piccirillo of McGill University, one of the study's authors. "For the last several years, it's been postulated that non-functional regulatory T-cells are the critical mechanism, and this study proves it."
The research was conducted on mice that were genetically engineered to model human diabetes. Piccirillo and colleagues discovered the functional potency of T-cells in the mice declined with age, leaving autoimmune responses in the pancreas unchecked. Piccirillo said that finding could lead to the development of immune system-based therapies for a range of diseases.
The study appears in the journal Diabetes.
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